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Isaac "Ike" Segel, the son of Russian immigrants, was born and lived in Toronto’s Ward district until 1900 when the family moved to Orillia, Ontario. Isaac recalls his experiences as one of three Jewish boys attending the local Orillia high school and working in his father’s general store. In order to provide a proper Jewish life for Isaac, the family returned to Toronto. In 1917 Isaac enlisted in the army and after his father’s death in 1918, Isaac made his home in Hamilton, Ontario. He was a business executive, active on several executive committees of Jewish and Zionist organizations in Hamilton.
Issac maried Esther Segal (née Kenen) who was influential in the National Council of Jewish Women, Hamilton Branch, and their successful attempt to repeal the law that refused the right of women to serve on jury duty.